SCHEMBL21541035

SCHEMBL21541035

CCCC(=O)N(C=O)OC=O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
FFAR3 O14843 3/20 0.32
HDAC3 O15379 3/20 0.32
HDAC1 Q13547 3/20 0.32
HDAC2 Q92769 3/20 0.32
HDAC8 Q9BY41 3/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12225351 0.83 SOAT1 (0.32) ALDH1A1TSHR
SCHEMBL14535262 0.81 ALDH1A1 (0.36) ALDH1A1CES2CES1FFAR3HDAC3
SCHEMBL13636953 0.78 ALDH1A1 (0.34) ALDH1A1CES2CES1FFAR3HDAC3
SCHEMBL19882382 0.76 ALDH1A1 (0.41) ALDH1A1CES2CES1FFAR3HDAC3
SCHEMBL22621253 0.76 TSHR (0.38) ALDH1A1CES2CES1FFAR3HDAC3
SCHEMBL24982752 0.75 GAPDH (0.31) ALDH1A1CES2CES1
SCHEMBL23007992 0.75 ALDH1A1 (0.31) ALDH1A1CES2CES1HDAC3HDAC1
SCHEMBL22043673 0.73 ALDH1A1 (0.30) ALDH1A1
SCHEMBL19003436 0.73 NPSR1 (0.36) ALDH1A1TSHR
SCHEMBL21443802 0.72 CES2 (0.36) ALDH1A1CES2CES1FFAR3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3560937-A1 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS Cancer Targeted Technology LLC (US) 2019-10-30 EP disclosed