SCHEMBL23008458

SCHEMBL23008458

C1=CCC(c2cccnc2)C=CC1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 9/20 0.50
CHRNA4 P43681 9/20 0.50
CHRNA7 P36544 5/20 0.50
CYP2A6 P11509 3/20 0.50
CYP11B2 P19099 1/20 0.43
MEN1 O00255 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11933858 0.81 CHRNB2 (0.47) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2
SCHEMBL4071841 0.75
SCHEMBL6543678 0.72 CYP11B2 (0.51) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2
SCHEMBL19529128 0.70 CYP2A6 (0.45) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2
SCHEMBL14401581 0.70 CHRNB2 (0.42) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2
SCHEMBL19594483 0.70 CHRNB2 (0.47) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2
SCHEMBL17525872 0.67 CYP11B2 (0.41) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2
SCHEMBL21755365 0.67 ESR2 (0.35) MEN1KMT2ACYP2C9
SCHEMBL3083734 0.67 CYP2A6 (0.49) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2
SCHEMBL27974093 0.67 CHRNB2 (0.49) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3780208-A1 FLOW BATTERY Panasonic Intellectual Property Management Co., Ltd. (JP) 2021-02-17 EP disclosed