SCHEMBL14401581

SCHEMBL14401581

CC1=CCC(c2cccnc2)C=C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 8/20 0.42
CHRNA4 P43681 8/20 0.42
CHRNA7 P36544 5/20 0.42
CYP2A6 P11509 3/20 0.42
ALDH1A1 P00352 2/20 0.42
CHRNB4 P30926 2/20 0.42
CHRNA3 P32297 2/20 0.42
CHRNA2 Q15822 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
HTR3E A5X5Y0 1/20 0.42
PSIP1 O75475 1/20 0.42
TRPA1 O75762 1/20 0.42
HTR3B O95264 1/20 0.42
CHRNA1 P02708 1/20 0.42
CHRNG P07510 1/20 0.42
CHRNB1 P11230 1/20 0.42
PTGS1 P23219 1/20 0.42
CHRNA5 P30532 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19529128 0.81 CYP2A6 (0.45) CHRNB2CHRNA4CHRNA7CYP2A6CHRNA3
SCHEMBL4071841 0.73
SCHEMBL11933858 0.71 CHRNB2 (0.47) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2
SCHEMBL29405711 0.71 MAPT (0.43) CHRNB2CHRNA4CHRNA7CYP2A6ALDH1A1
SCHEMBL22780690 0.71 PTPN1 (0.36) ALDH1A1MAPTLMNA
SCHEMBL23008458 0.70 CHRNB2 (0.50) CHRNB2CHRNA4CHRNA7CYP2A6CYP11B2
SCHEMBL27471552 0.70 CYP11B2 (0.51) CHRNB2CHRNA4CHRNA7CYP2A6ALDH1A1
SCHEMBL30317862 0.70 CYP11B2 (0.44) CHRNB2CHRNA4CHRNA7CYP2A6ALDH1A1
SCHEMBL23193433 0.66 CYP11B2 (0.42) CYP2A6ALDH1A1PSIP1CYP11B2
SCHEMBL8639636 0.66 GABRP (0.34) CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847525-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-10-24 EP disclosed