Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18965092 | 0.78 | FAAH (0.47) | TSHRSMN1; SMN2FAAHALDH1A1RECQL | |
| SCHEMBL18965507 | 0.73 | CYP2D6 (0.43) | SMN1; SMN2MAPTRECQL | |
| SCHEMBL22454282 | 0.73 | ALDH1A1 (0.34) | TSHRFAAHALDH1A1RECQL | |
| SCHEMBL16710792 | 0.73 | CNR2 (0.34) | SMN1; SMN2RECQL | |
| SCHEMBL19992543 | 0.73 | LMNA (0.44) | ALDH1A1 | |
| SCHEMBL871580 | 0.73 | — | — | |
| SCHEMBL12838131 | 0.71 | LMNA (0.43) | TSHRSMN1; SMN2MAPTFAAHALDH1A1 | |
| SCHEMBL12959555 | 0.71 | HPGD (0.42) | TSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14391566 | 0.71 | ALDH1A1 (0.46) | TSHRSMN1; SMN2MAPTFAAHALDH1A1 | |
| SCHEMBL14397823 | 0.70 | PHF8 (0.50) | TSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778602-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |