Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942514 | 0.89 | ALDH1A1 (0.47) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL24029280 | 0.83 | KDM4E (0.43) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL3469723 | 0.83 | KMT2A (0.58) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL7052702 | 0.77 | GRM2 (0.40) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL6695252 | 0.76 | KDM4E (0.54) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL7056204 | 0.76 | LMNA (0.50) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL3470444 | 0.74 | KDM4E (0.58) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL7052739 | 0.71 | F2 (0.48) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL26173847 | 0.71 | NPSR1 (0.43) | KMT2AKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL2330079 | 0.70 | ALDH1A1 (0.56) | KMT2AMEN1KDM4EALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210045387-A1 | COMPOSITIONS AND METHODS TO INHIBIT ARTHROPOD HOST-SEEKING BEHAVIOR | THE ROCKEFELLER UNIVERSITY (US) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210045387-A1 | COMPOSITIONS AND METHODS TO INHIBIT ARTHROPOD HOST-SEEKING BEHAVIOR | CHIA, CFH, C5 | KMT2A 2355/4885MEN1 2088/4885KDM4E 3506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.