Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | ST6GAL1 | P15907 | 5/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18102346 | 0.89 | POLG (0.54) | POLGPOLBLMNACACNA1FALB | |
| SCHEMBL6913592 | 0.87 | POLG (0.49) | POLGPOLBLMNACACNA1FALB | |
| SCHEMBL1763274 | 0.84 | POLG (0.59) | POLGPOLBLMNACACNA1FALB | |
| SCHEMBL21895844 | 0.84 | POLG (0.55) | POLGPOLBLMNACACNA1FALB | |
| SCHEMBL23157013 | 0.84 | POLG (0.55) | POLGPOLBLMNACACNA1FALB | |
| SCHEMBL23157216 | 0.84 | POLG (0.55) | POLGPOLBLMNACACNA1FALB | |
| SCHEMBL454264 | 0.84 | POLG (0.55) | POLGPOLBLMNACACNA1FALB | |
| SCHEMBL24229283 | 0.82 | LMNA (0.46) | POLGPOLBLMNACACNA1FALB | |
| SCHEMBL26795253 | 0.82 | LMNA (0.46) | POLGPOLBLMNACACNA1FALB | |
| SCHEMBL15257625 | 0.82 | LMNA (0.46) | POLGPOLBLMNACACNA1FALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935303-B1 | 4'-FLUORO-NUCLEOSIDES, 4'-FLUORO-NUCLEOTIDES AND ANALOGS THEREOF FOR THE TREATMENT OF HCV | JANSSEN BIOPHARMA INC (US) | 2021-02-17 | — | — | EP | disclosed |