Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19035716 | 0.88 | HPGD (0.61) | HINT1HPGDNT5EGSK3ARPS6KA3 | |
| SCHEMBL14003429 | 0.87 | HINT1 (0.57) | HINT1HPGDNT5EGSK3ARPS6KA3 | |
| SCHEMBL13899230 | 0.87 | HINT1 (0.57) | HINT1HPGDNT5EGSK3ARPS6KA3 | |
| SCHEMBL19035717 | 0.84 | HINT1 (0.52) | HINT1HPGDNT5EGSK3ARPS6KA3 | |
| SCHEMBL16807574 | 0.83 | HINT1 (0.63) | HINT1HPGDNT5EGSK3ARPS6KA3 | |
| SCHEMBL26540650 | 0.82 | HINT1 (0.58) | HINT1HPGDNT5EGSK3ARPS6KA3 | |
| SCHEMBL1115914 | 0.82 | HPGD (0.62) | HINT1HPGDNT5EGSK3ARPS6KA3 | |
| SCHEMBL14143259 | 0.82 | HPGD (0.62) | HINT1HPGDNT5EGSK3ARPS6KA3 | |
| SCHEMBL19831524 | 0.82 | HPGD (0.62) | HINT1HPGDNT5EGSK3ARPS6KA3 | |
| SCHEMBL6839232 | 0.82 | HINT1 (0.59) | HINT1HPGDNT5EGSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935303-B1 | 4'-FLUORO-NUCLEOSIDES, 4'-FLUORO-NUCLEOTIDES AND ANALOGS THEREOF FOR THE TREATMENT OF HCV | JANSSEN BIOPHARMA INC (US) | 2021-02-17 | — | — | EP | disclosed |