Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | UTRN | P46939 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012925 | 0.90 | ALDH1A1 (0.61) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29479804 | 0.90 | ALDH1A1 (0.61) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL23034143 | 0.86 | MAPT (0.71) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL23012520 | 0.83 | KDM4E (0.64) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL31165939 | 0.83 | KDM4E (0.64) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL28701684 | 0.83 | ALDH1A1 (0.71) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL23033654 | 0.82 | MAPT (0.54) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL23033327 | 0.81 | MAPT (0.53) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL23012893 | 0.81 | MAPT (0.53) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29479624 | 0.81 | MAPT (0.53) | NPC1ALDH1A1HPGDRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |