Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.65 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.43 |
| ▸ | WNT1 | P04628 | 10/20 | 0.43 |
| ▸ | GSK3B | P49841 | 10/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033561 | 0.82 | PIM1 (0.55) | PIM1PIM2DYRK1AWNT1GSK3B | |
| SCHEMBL23033587 | 0.80 | GSK3B (0.43) | DYRK1AWNT1GSK3B | |
| SCHEMBL28714669 | 0.69 | PIM1 (0.40) | PIM1PIM2S1PR1 | |
| SCHEMBL2108962 | 0.69 | CCNC (0.56) | PIM1PIM2DYRK1AWNT1GSK3B | |
| SCHEMBL23033375 | 0.69 | NPC1 (0.47) | ABL1 | |
| SCHEMBL28714630 | 0.69 | KDM4E (0.44) | PIM1PIM2DYRK1AWNT1GSK3B | |
| SCHEMBL28706416 | 0.69 | MAOA (0.43) | PIM1PIM2 | |
| SCHEMBL23012523 | 0.69 | GSK3B (0.45) | DYRK1AWNT1GSK3B | |
| SCHEMBL29479615 | 0.69 | MAOA (0.43) | PIM1PIM2 | |
| SCHEMBL29961343 | 0.68 | CLK2 (0.56) | PIM1PIM2DYRK1AWNT1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |