Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160728 | 0.73 | AHR (0.63) | KIF11ALDH1A1HSD17B10GPR3AHR | |
| SCHEMBL9010052 | 0.72 | KIF11 (0.49) | KIF11ALDH1A1HSD17B10GPR3AHR | |
| SCHEMBL1427044 | 0.70 | MAPT (0.46) | KIF11ALDH1A1HSD17B10GPR3AHR | |
| SCHEMBL10616131 | 0.67 | ALDH1A1 (0.45) | KIF11ALDH1A1HSD17B10GPR3AHR | |
| SCHEMBL3866477 | 0.66 | KIF11 (1.00) | KIF11ALDH1A1HSD17B10GPR3AHR | |
| SCHEMBL1426545 | 0.66 | KIF11 (0.48) | KIF11ALDH1A1HSD17B10GPR3AHR | |
| SCHEMBL29361061 | 0.66 | KIF11 (1.00) | KIF11ALDH1A1HSD17B10GPR3AHR | |
| SCHEMBL5216846 | 0.66 | KIF11 (0.49) | KIF11ALDH1A1HSD17B10GPR3AHR | |
| SCHEMBL667987 | 0.65 | KIF11 (0.39) | KIF11ALDH1A1HSD17B10GPR3AHR | |
| SCHEMBL15828556 | 0.65 | CYP1A2 (0.61) | KIF11ALDH1A1HSD17B10GPR3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017862-A1 | BIS(PHOSPHINO)-PHENOXY NICKEL(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND ACRYLATE MONOMERS | Dow Global Technologies LLC (US) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021034809-A1 | BIS(PHOSPHINO)-PHENOXY NICKEL(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND ACRYLATE MONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-02-25 | — | — | WO | disclosed |