SCHEMBL1426545

SCHEMBL1426545

Cc1[c]c2[nH]c3ccccc3c2cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.48
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 4/20 0.48
GPR3 P46089 2/20 0.48
AHR P35869 2/20 0.44
CYP1A2 P05177 4/20 0.43
GAA P10253 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
TNKS2 Q9H2K2 2/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
BLM P54132 2/20 0.40
GABRP O00591 2/20 0.40
GABRD O14764 2/20 0.40
GABRA1 P14867 2/20 0.40
HPGD P15428 2/20 0.40
GABRB1 P18505 2/20 0.40
GABRG2 P18507 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5216846 0.80 KIF11 (0.49) KIF11ALDH1A1HSD17B10GPR3AHR
SCHEMBL17784174 0.77 KIF11 (0.46) KIF11ALDH1A1HSD17B10GPR3AHR
SCHEMBL7953010 0.77 ALDH1A1 (0.48) KIF11ALDH1A1HSD17B10GPR3AHR
SCHEMBL8482653 0.77 ALDH1A1 (0.48) KIF11ALDH1A1HSD17B10GPR3AHR
SCHEMBL10890967 0.77 ALDH1A1 (0.48) KIF11ALDH1A1HSD17B10GPR3AHR
SCHEMBL23212272 0.77 ALDH1A1 (0.48) KIF11ALDH1A1HSD17B10GPR3AHR
SCHEMBL11597870 0.77 ALDH1A1 (0.48) KIF11ALDH1A1HSD17B10GPR3AHR
SCHEMBL6897737 0.77 ALDH1A1 (0.45) KIF11ALDH1A1HSD17B10GPR3AHR
SCHEMBL9010052 0.77 KIF11 (0.49) KIF11ALDH1A1HSD17B10GPR3AHR
SCHEMBL1427044 0.74 MAPT (0.46) KIF11ALDH1A1HSD17B10GPR3AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113105420-A Fused ring arylamine compound, application thereof and organic electroluminescent device containing compound 浙江虹舞科技有限公司 2021-07-13 CN claimed
US-9164406-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-10-20 US claimed
US-20140205941-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-07-24 US claimed
EP-2757420-A1 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2014-07-23 EP claimed
CN-115109064-B Heterocyclic compound and organic electroluminescent device 武汉天马微电子有限公司 2023-11-14 CN disclosed
CN-113105420-B Condensed ring arylamine compound, application thereof and organic electroluminescent device containing compound 浙江虹舞科技有限公司 2023-06-16 CN disclosed
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-05-18 US disclosed
CN-115109064-A Heterocyclic compound and organic electroluminescent device 武汉天马微电子有限公司 2022-09-27 CN disclosed
CN-109548404-B Propylene-alpha olefin copolymer and process for producing the same 埃克森美孚化学专利公司 2022-02-08 CN disclosed
US-11192961-B2 Production of heterophasic polymers in gas or slurry phase EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-07 US disclosed
CN-113666963-A Compound, display panel and display device 武汉天马微电子有限公司 2021-11-19 CN disclosed
EP-3885373-A1 PRODUCTION OF HETEROPHASIC POLYMERS IN GAS OR SLURRY PHASE ExxonMobil Chemical Patents Inc. (US) 2021-09-29 EP disclosed
US-8859110-B2 Cyclic phosphazene compounds and use thereof in organic light emitting diodes BASF SE (DE) 2014-10-14 US disclosed
US-20140205941-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-07-24 US disclosed
EP-2757420-A1 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2014-07-23 EP disclosed
EP-2301091-B1 USE OF CYCLIC PHOSPHAZENE COMPOUNDS IN ORGANIC LIGHT EMITTING DIODES BASF SE (DE) 2013-08-21 EP disclosed
US-20110172423-A1 CYCLIC PHOSPHAZENE COMPOUNDS AND USE THEREOF IN ORGANIC LIGHT EMITTING DIODES BASF SE (DE) 2011-07-14 US disclosed
EP-2301091-A1 CYCLIC PHOSPHAZENE COMPOUNDS AND USE THEREOF IN ORGANIC LIGHT EMITTING DIODES BASF SE (DE) 2011-03-30 EP disclosed
WO-2009153276-A1 CYCLIC PHOSPHAZENE COMPOUNDS AND USE THEREOF IN ORGANIC LIGHT EMITTING DIODES BASF SE (DE) 2009-12-23 WO disclosed
EP-0741145-A1 Olefin polymerization catalyst and process for producing polyolefin using the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172423-A1 CYCLIC PHOSPHAZENE COMPOUNDS AND USE THEREOF IN ORGANIC LIGHT EMITTING DIODES PHOSPHO1, PDE6B, PDE6C KIF11 4422/4885ALDH1A1 1196/4885HSD17B10 3822/4885
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE OCIAD1, OCIAD2, EHD1 KIF11 1608/4885ALDH1A1 686/4885HSD17B10 652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.