Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ASPH | Q12797 | 2/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.48 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724596 | 0.90 | HDAC8 (0.47) | VNN1MEN1KMT2AMAPTCD38 | |
| SCHEMBL21617346 | 0.90 | HDAC8 (0.47) | VNN1MEN1KMT2AMAPTCD38 | |
| SCHEMBL4976162 | 0.84 | PDE5A (0.49) | PDE5AALDH1A1 | |
| SCHEMBL26663224 | 0.84 | ALDH1A1 (0.40) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL27007123 | 0.83 | KDM4C (0.53) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29922728 | 0.83 | KDM4C (0.53) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29692343 | 0.81 | PDE5A (0.50) | KDM4EASPHKDM8RIOX2MEN1 | |
| SCHEMBL23015389 | 0.81 | PDE5A (0.50) | KDM4EASPHKDM8RIOX2MEN1 | |
| SCHEMBL21723070 | 0.79 | KDM4E (0.56) | KDM4EASPHKDM8RIOX2VNN1 | |
| SCHEMBL29976764 | 0.79 | KDM4E (0.56) | KDM4EASPHKDM8RIOX2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017593-B1 | BICYCLIC AGONISTS OF STIMULATOR OF INTERFERON GENES STING | SCRIPPS RESEARCH INST (US) | 2025-07-23 | — | — | EP | disclosed |
| US-20250221987-A1 | PIPERAZINO RING-CONTAINING DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | ACERAND THERAPEUTICS (HONG KONG) LIMITED (CN) | 2025-07-10 | — | — | US | disclosed |
| WO-2025011494-A1 | CRYSTAL FORM OF PIPERAZINO RING-CONTAINING DERIVATIVE, SALT FORM, PREPARATION METHOD, AND USE | 优领医药科技(香港)有限公司 | 2025-01-16 | — | — | WO | disclosed |
| EP-4464704-A1 | PIPERAZINO RING-CONTAINING DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Acerand Therapeutics (Hong Kong) Limited (HK) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023134647-A1 | PIPERAZINO RING-CONTAINING DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 优领医药科技(香港)有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023134647-A1 | PIPERAZINO RING-CONTAINING DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 优领医药科技(香港)有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-116425744-A | Piperazine-containing ring derivative, pharmaceutically acceptable salt thereof, and preparation method and application thereof | 优领医药科技(香港)有限公司 | 2023-07-14 | — | — | CN | disclosed |
| US-20220332720-A1 | BICYCLIC AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE | 2022-10-20 | — | — | US | disclosed |
| CN-115003383-A | Bicyclic agonists of interferon gene stimulator STING | 斯克里普斯研究学院 | 2022-09-02 | — | — | CN | disclosed |
| EP-4017593-A1 | BICYCLIC AGONISTS OF STIMULATOR OF INTERFERON GENES STING | The Scripps Research Institute (US) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021035258-A1 | BICYCLIC AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250221987-A1 | PIPERAZINO RING-CONTAINING DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | PARP1, PARP11, PARP15 | KDM4E 1630/4885ASPH 1821/4885KDM8 772/4885 |
| US-20220332720-A1 | BICYCLIC AGONISTS OF STIMULATOR OF INTERFERON GENES STING | STING1, IRF3, IFNAR1 | KDM4E 1800/4885ASPH 4713/4885KDM8 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.