Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617346 | 1.00 | HDAC8 (0.47) | HDAC8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23015337 | 0.90 | KDM4E (0.48) | MAPTALDH1A1MEN1KMT2AVNN1 | |
| SCHEMBL26663224 | 0.86 | ALDH1A1 (0.40) | HDAC8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2133084 | 0.86 | MEN1 (0.47) | HDAC8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4976162 | 0.84 | PDE5A (0.49) | ALDH1A1GAA | |
| SCHEMBL21617360 | 0.84 | SYK (0.49) | HDAC8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4212317 | 0.84 | HPGD (0.48) | HDAC8MAPTKMT2ANPSR1LMNA | |
| SCHEMBL31038753 | 0.79 | HDAC8 (0.47) | HDAC8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29206801 | 0.77 | HTR6 (0.46) | HDAC8MAPTALDH1A1LMNARAB9A | |
| SCHEMBL30904789 | 0.77 | HTR6 (0.46) | HDAC8MAPTALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112584898-B | P2X 3 Receptor antagonists | 瑞蔻达蒂化学和制药工业股份有限公司 | 2024-01-26 | — | — | CN | disclosed |