Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.95 |
| ▸ | CA9 | Q16790 | 11/20 | 0.95 |
| ▸ | CA1 | P00915 | 7/20 | 0.95 |
| ▸ | CA3 | P07451 | 7/20 | 0.95 |
| ▸ | CA4 | P22748 | 7/20 | 0.95 |
| ▸ | CA7 | P43166 | 7/20 | 0.95 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.95 |
| ▸ | CA5A | P35218 | 6/20 | 0.95 |
| ▸ | CA6 | P23280 | 6/20 | 0.95 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.95 |
| ▸ | CA2 | P00918 | 5/20 | 0.95 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.95 |
| ▸ | LMNA | P02545 | 3/20 | 0.95 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.95 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumarin SCHEMBL29385611 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL6252 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL28886137 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL1038138 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL621751 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL3441294 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL8004826 | 0.95 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL531571 | 0.95 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL22721260 | 0.95 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL9643642 | 0.95 | CA12 (0.95) | CA12CA9CA1CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272399-A | The method of biomass-based furfuryl alcohol derivative green high-efficient synthesis Coumarin methane | 诸暨市瀚海环保科技有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-110483460-B | Preparation method of 3-seleno-coumarin compound | 温州医科大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-110831969-A | Methods of treating or ameliorating metabolic disorders using a combination of a Gastric Inhibitory Peptide Receptor (GIPR) binding protein and a GLP-1 agonist | 安进公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110437182-A | A method of BMFM is synthesized from 5-MFA green high-efficient | UNIV NANCHANG | 2019-11-12 | — | — | CN | disclosed |
| CN-110272399-A | The method of biomass-based furfuryl alcohol derivative green high-efficient synthesis Coumarin methane | 诸暨市瀚海环保科技有限公司 | 2019-09-24 | — | — | CN | disclosed |
| CN-110272399-A | The method of biomass-based furfuryl alcohol derivative green high-efficient synthesis Coumarin methane | 诸暨市瀚海环保科技有限公司 | 2019-09-24 | — | — | CN | disclosed |
| CN-110272399-A | The method of biomass-based furfuryl alcohol derivative green high-efficient synthesis Coumarin methane | 诸暨市瀚海环保科技有限公司 | 2019-09-24 | — | — | CN | disclosed |
| US-8313920-B2 | High-throughput assay for evaluating dipeptidyl peptidase I activity | JANSSEN RESEARCH & DEVELOPMENT, LLC (US) | 2012-11-20 | — | — | US | disclosed |
| EP-2350310-A1 | HIGH-THROUGHPUT ASSAY FOR EVALUATING DIPEPTIDYL PEPTIDASE I ACTIVITY | Johnson & Johnson Pharmaceutical Research & Development L.L.C. (US) | 2011-08-03 | — | — | EP | disclosed |
| US-20100136594-A1 | HIGH-THROUGHPUT ASSAY FOR EVALUATING DIPEPTIDYL PEPTIDASE I ACTIVITY | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, LLC (US) | 2010-06-03 | — | — | US | disclosed |
| WO-2010048306-A1 | HIGH-THROUGHPUT ASSAY FOR EVALUATING DIPEPTIDYL PEPTIDASE I ACTIVITY | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C. (US) | 2010-04-29 | — | — | WO | disclosed |