Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17903494 | 0.98 | OPRM1 (0.48) | OPRM1ALDH1A1TDP1SPHK1DNM1 | |
| SCHEMBL18124690 | 0.92 | ALDH1A1 (0.54) | OPRM1ALDH1A1TDP1SPHK1DNM1 | |
| SCHEMBL4857794 | 0.92 | ALDH1A1 (0.54) | OPRM1ALDH1A1TDP1SPHK1DNM1 | |
| SCHEMBL24138702 | 0.82 | OPRM1 (0.43) | OPRM1ALDH1A1TDP1SPHK1TP53 | |
| SCHEMBL28202256 | 0.81 | OPRM1 (0.50) | OPRM1SPHK1TP53DNM1TSHR | |
| SCHEMBL6606474 | 0.81 | OPRM1 (0.50) | OPRM1SPHK1TP53DNM1TSHR | |
| SCHEMBL28291438 | 0.81 | OPRM1 (0.50) | OPRM1SPHK1TP53DNM1TSHR | |
| SCHEMBL11333881 | 0.81 | OPRM1 (0.50) | OPRM1SPHK1TP53DNM1TSHR | |
| SCHEMBL5932767 | 0.81 | — | — | |
| SCHEMBL3626376 | 0.81 | OPRM1 (0.46) | OPRM1ALDH1A1TDP1SPHK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | PHARMASUM THERAPEUTICS AS (NO) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | DYRK1A, DYRK1B, PDK2 | OPRM1 4421/4885ALDH1A1 1092/4885TDP1 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.