Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 17/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23015734 | 0.84 | HRH4 (0.39) | TRPV3HRH4 | |
| SCHEMBL14454179 | 0.79 | HRH4 (0.43) | TRPV3HRH4 | |
| SCHEMBL23015683 | 0.77 | TRPV3 (0.38) | TRPV3ADRA2C | |
| SCHEMBL12190563 | 0.77 | SORD (0.39) | HRH4 | |
| SCHEMBL16815429 | 0.76 | CCR1 (0.39) | TRPV3HRH4 | |
| SCHEMBL18559669 | 0.76 | NOS3 (0.35) | HRH4 | |
| SCHEMBL15274637 | 0.76 | HRH4 (0.35) | TRPV3HRH4 | |
| SCHEMBL8819724 | 0.76 | HRH4 (0.35) | HRH4 | |
| SCHEMBL12190564 | 0.74 | KDM4E (0.39) | HRH4 | |
| SCHEMBL23542736 | 0.73 | AAK1 (0.35) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | PHARMASUM THERAPEUTICS AS (NO) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | DYRK1A, DYRK1B, PDK2 | TRPV3 3145/4885HRH4 4127/4885ADRA2C 2604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.