Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24475370 | 0.97 | TNF (0.41) | TNFPIK3CANPC1RAB9APOLB | |
| SCHEMBL24475417 | 0.93 | TNF (0.44) | TNFPIK3CANPC1RAB9ACCR1 | |
| SCHEMBL23016208 | 0.92 | PIK3CA (0.40) | TNFPIK3CANPC1RAB9APOLB | |
| SCHEMBL23016292 | 0.91 | TNF (0.41) | TNFPIK3CANPC1RAB9APOLB | |
| SCHEMBL23016133 | 0.91 | TNF (0.42) | TNFPIK3CANPC1RAB9APOLB | |
| SCHEMBL24454297 | 0.90 | TNF (0.43) | TNFPIK3CACCR1CCR5CCR8 | |
| SCHEMBL23016197 | 0.90 | TOP1 (0.40) | PIK3CANPC1RAB9APOLBCCR1 | |
| SCHEMBL23016087 | 0.89 | NPC1 (0.45) | PIK3CANPC1RAB9APOLBCCR1 | |
| SCHEMBL24475579 | 0.89 | PIK3CA (0.38) | PIK3CANPC1RAB9APOLBCCR1 | |
| SCHEMBL23016178 | 0.88 | NPC1 (0.42) | PIK3CANPC1RAB9APOLBCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10930857-B2 | Heterocyclic compound and organic light emitting device using same | LT MATERIALS CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10930857-B2 | Heterocyclic compound and organic light emitting device using same | CRY1, CRY2, CYBA | TNF 1871/4885PIK3CA 3123/4885NPC1 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.