Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28114546 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| Acetic Acid SCHEMBL8775549 | 0.96 | TSHR (0.47) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| SCHEMBL28226548 | 0.96 | TSHR (0.50) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| SCHEMBL1057516 | 0.96 | TSHR (0.50) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| SCHEMBL4823985 | 0.96 | — | — | |
| SCHEMBL8921614 | 0.96 | — | — | |
| SCHEMBL22017 | 0.96 | — | — | |
| SCHEMBL6269152 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL655219 | 0.94 | TSHR (0.45) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| Methacrylic Acid SCHEMBL250051 | 0.94 | TSHR (0.45) | TSHRTHRBALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12272811-B2 | Method of manufacturing battery electrode | NISSAN MOTOR CO., LTD. (JP) | 2025-04-08 | — | — | US | disclosed |
| WO-2025047391-A1 | POSITIVE ELECTRODE FOR LITHIUM SECONDARY BATTERIES AND LITHIUM SECONDARY BATTERY USING SAME | 日産自動車株式会社 | 2025-03-06 | — | — | WO | disclosed |
| EP-4501303-A2 | INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE | Solventum Intellectual Properties Company (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2024252161-A1 | ELECTRODE FOR NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY | 日産自動車株式会社 | 2024-12-12 | — | — | WO | disclosed |
| US-12051803-B2 | Negative electrode for non-aqueous electrolyte secondary battery and non-aqueous electrolyte secondary battery using the same | NISSAN MOTOR CO., LTD. (JP) | 2024-07-30 | — | — | US | disclosed |
| CN-112204801-B | Battery device | 日产自动车株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-3866223-B1 | NEGATIVE ELECTRODE FOR NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME | NISSAN MOTOR (JP) | 2024-06-05 | — | — | EP | disclosed |
| EP-3696891-B1 | METHOD FOR PRODUCING ELECTRODE FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY | NISSAN MOTOR (JP) | 2024-04-17 | — | — | EP | disclosed |
| US-11935998-B2 | Battery device | NISSAN MOTOR CO., LTD. (JP) | 2024-03-19 | — | — | US | disclosed |
| EP-3696887-B1 | ELECTRODE FOR NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY | NISSAN MOTOR (JP) | 2023-12-27 | — | — | EP | disclosed |
| EP-1059323-A1 | THERMOSETTING COMPOSITION CONTAINING POLYHEMIACETAL ESTER RESIN AND POWDERY THERMOSETTING COMPOSITION | NOF CORPORATION (JP) | 2000-12-13 | — | — | EP | disclosed |
| US-6103387-A | THERMOSETTING RESIN COMPRISING A CERAMIC, WHICH GIVES A CURED PRODUCT HAVING EXCELLENT STAIN RESISTANCE, STAIN-REMOVING PROPERTY, WEATHERING RESISTANCE, LIGHT RESISTANCE, CHEMICAL RESISTANCE, MOISTURE RESISTANCE AND APPEARANCE | NOF CORPORATION (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0992549-A1 | ANTIFOULING AGENT, METHOD FOR ANTIFOULING TREATMENT, AND ARTICLE OBTAINED THROUGH ANTIFOULING TREATMENT | NOF CORPORATION (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-6030571-A | Methods of molding and molded articles made thereby | NOF CORPORATION (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5922633-A | THERMAL LATENT ACID CATALYST CONSISTS OF AN EPOXY COMPOUND, A SULFUR COMPOUND AND LEWIS ACID | NOF CORPORATION (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0805186-A1 | THERMOSETTING COMPOSITION, METHOD OF FINISH COATING, AND COATED ARTICLES | NOF CORPORATION (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5661219-A | AN ACRYLIC COPOLYMER HAVING CARBOXY GROUPS BLOCKED BY A VINYL ETHER, A REACTIVE POLYMER, E.G.HAVING EPOXY GROUPS, AND LEWIS ACID-COMPLEX CATALYST; HIGH SOLIDS; LOW TEMPERATURE CURING; STORAGE STABILITY; MECHANICAL PROPERTIES | NOF CORPORATION (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0643112-B1 | Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article | NOF CORP (JP) | 1997-07-30 | — | — | EP | disclosed |
| EP-0709415-A2 | Curable base-coat composition, method of film-forming and coated articles | NOF CORPORATION (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0643112-A2 | Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article | NOF CORPORATION (JP) | 1995-03-15 | — | — | EP | disclosed |