Methacrylic Acid

Methacrylic Acid

SCHEMBL655219

C=C(C)C(=O)O.C=C(C)C(=O)O.C=CCOC(=O)C(=C)C

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.45
THRB P10828 1/20 0.42
ALDH1A1 P00352 5/20 0.40
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
MAPT P10636 3/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
HSD17B10 Q99714 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL250051 1.00 TSHR (0.45) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL11017971 0.98 TSHR (0.44) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL460950 0.98 TSHR (0.44) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL28243084 0.94 TSHR (0.41) TSHRTHRBALDH1A1CYP3A4TDP1
Bicarbonate SCHEMBL2301694 0.94 TSHR (0.47) TSHRTHRBALDH1A1CYP3A4TDP1
Acetic Acid SCHEMBL8775549 0.94 TSHR (0.47) TSHRTHRBALDH1A1CYP3A4TDP1
Bicarbonate SCHEMBL28114546 0.94 TSHR (0.47) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL1057516 0.94 TSHR (0.50) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL6269152 0.94
SCHEMBL22017 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090285866-A1 Self-healing polymer compositions ELC MANAGEMENT LLC 2009-11-19 US claimed
WO-2008154107-A1 SELF-HEALING POLYMER COMPOSITIONS ELC MANAGEMENT LLC (US) 2008-12-18 WO claimed
WO-2007018736-A2 ENCAPSULATED STRUCTURAL ADHESIVE APPLETON PAPERS INC. (US) 2007-02-15 WO claimed
US-20070021533-A1 Encapsulated structural adhesive APPLETON PAPERS INC. (US) 2007-01-25 US claimed
EP-1360069-A4 IN SITU MICROENCAPSULATED ADHESIVE APPLETON PAPER INC (US) 2006-05-10 EP claimed
EP-1360069-A2 IN SITU MICROENCAPSULATED ADHESIVE Appleton Papers Inc. (US) 2003-11-12 EP claimed
US-6592990-B2 Pressure sensitive or flowable APPLETON PAPERS INC. 2003-07-15 US claimed
US-20020169233-A1 In situ microencapsulated adhesive IPS ADHESIVES LLC 2002-11-14 US claimed
WO-2002020683-A2 IN SITU MICROENCAPSULATED ADHESIVE APPLETON PAPERS INC. (US) 2002-03-14 WO claimed
EP-3455285-A1 SPRAY APPLIED INSULATIVE AND PROTECTIVE COATING SWIMC LLC (US) 2019-03-20 EP disclosed
WO-2017197069-A1 SPRAY APPLIED INSULATIVE AND PROTECTIVE COATING THE SHERWIN-WILLIAMS COMPANY (US) 2017-11-16 WO disclosed
EP-1863634-B1 ADHESIVELY SECURABLE STOCK MATERIALS ENCAPSYS LLC (US) 2017-03-29 EP disclosed
EP-1861246-B1 ADHESIVELY SECURABLE STOCK PACKAGING MATERIALS ENCAPSYS LLC (US) 2017-03-29 EP disclosed
EP-1784302-B1 ENCAPSULATED CURE SYSTEMS ENCAPSYS LLC (US) 2016-07-06 EP disclosed
US-20060073334-A1 Encapsulated cure systems IPS STRUCTURAL ADHESIVES, INC. 2006-04-06 US disclosed
WO-2006028806-A2 ENCAPSULATED CURE SYSTEMS APPLETON PAPERS INC. (US) 2006-03-16 WO disclosed
EP-1360069-A2 IN SITU MICROENCAPSULATED ADHESIVE Appleton Papers Inc. (US) 2003-11-12 EP disclosed
US-6592990-B2 Pressure sensitive or flowable APPLETON PAPERS INC. 2003-07-15 US disclosed
US-20020169233-A1 In situ microencapsulated adhesive IPS ADHESIVES LLC 2002-11-14 US disclosed
WO-2002020683-A2 IN SITU MICROENCAPSULATED ADHESIVE APPLETON PAPERS INC. (US) 2002-03-14 WO disclosed