Methacrylic Acid

Methacrylic Acid

SCHEMBL250051

C=C(C)C(=O)O.C=CCOC(=O)C(=C)C

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.45
THRB P10828 1/20 0.42
ALDH1A1 P00352 5/20 0.40
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
MAPT P10636 3/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
HSD17B10 Q99714 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL655219 1.00 TSHR (0.45) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL11017971 0.98 TSHR (0.44) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL460950 0.98 TSHR (0.44) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL28243084 0.94 TSHR (0.41) TSHRTHRBALDH1A1CYP3A4TDP1
Bicarbonate SCHEMBL2301694 0.94 TSHR (0.47) TSHRTHRBALDH1A1CYP3A4TDP1
Acetic Acid SCHEMBL8775549 0.94 TSHR (0.47) TSHRTHRBALDH1A1CYP3A4TDP1
Bicarbonate SCHEMBL28114546 0.94 TSHR (0.47) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL1057516 0.94 TSHR (0.50) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL6269152 0.94
SCHEMBL22017 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110859755-B Marrow covering agent for treating dental pulp lesions, and preparation method and application thereof 中国科学院化学研究所 2024-05-17 CN claimed
CN-117693320-A Large block for manufacturing dental prosthesis 株式会社哈斯 2024-03-12 CN claimed
CN-117624506-A 3D printing photosensitive resin and preparation method and application thereof 深圳市智能派科技有限公司 2024-03-01 CN claimed
WO-2023198738-A1 COATING COMPOSITIONS OF ISOCYANATES AND BASIC METAL COMPOUNDS SIKA TECHNOLOGY AG (CH) 2023-10-19 WO claimed
WO-2023166261-A1 PLASTIC SCINTILLATORS DISCRIMINATING BETWEEN ALPHA RADIATION AND BETA RADIATION EMITTED BY A RADIOACTIVE MEDIUM AND METHOD FOR DISCRIMINATING BETWEEN ALPHA RADIATION AND BETA RADIATION USING SAID SCINTILLATORS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-09-07 WO claimed
EP-3853638-A1 CYCLOPHANES AS AGENTS FOR DISCRIMINATING BETWEEN NEUTRONS AND GAMMA RAYS IN A PLASTIC SCINTILLATOR Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2021-07-28 EP claimed
CN-112566608-A Dental composition 斯蒂克技术公司 2021-03-26 CN claimed
EP-3532508-A1 PRODUCTION OF A POLYMER EMULSION Coatex (FR) 2019-09-04 EP claimed
CN-106590245-A Novel energy-saving environment-friendly wall paint and preparation method thereof 天津新基斯科技有限公司 2017-04-26 CN claimed
CN-106590231-A Energy-saving environment-friendly interior wall paint and preparation method thereof 天津新基斯科技有限公司 2017-04-26 CN claimed
CN-1269514-A Light diffusion composite material ATOCHEM ELF SA (FR) 2000-10-11 CN claimed
EP-0582223-B1 Thermoplastic resin composition KANEGAFUCHI CHEMICAL IND (JP) 1996-10-09 EP claimed
EP-0582223-A1 Thermoplastic resin composition KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1994-02-09 EP claimed
EP-0494481-A1 Coating composition of acrylic polymers containing reactive groups and an epoxy organosilane E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-15 EP claimed
EP-0483420-A1 Coating composition of an acrylic polymer containing glycidyl groups and acetoacetoxy groups and an amino ester acrylic polymer E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-06 EP claimed
US-4988759-A Room temperature curable polymer solution of solvent and an acrylic polymer as binders E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-29 US claimed
US-4987177-A AUTOMOBILE AND TRUCK FINISHES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-22 US claimed
US-4766012-A DISSOLVING COATING BY SALT FORMATION, DISPERSION OF DRUG PARTICLES, ACIDIFICATION TO PRECIPITATE COATING FARMACEUTICI FORMENTI S.P.A. (IT) 1988-08-23 US claimed
US-4225473-A Alkyd-monomer high-solids coating process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-09-30 US claimed
US-3968277-A Process for coating solid particles with a digestive tract-soluble film ZENYAKU KOGYO KABUSHIKI KAISHA (JA) 1976-07-06 US claimed