SCHEMBL23017166

SCHEMBL23017166

CCN(N)c1ccc(Br)c(Cl)c1N

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.37
ALDH1A3 P47895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20289209 0.80 ALDH1A3 (0.31) ALDH1A3
SCHEMBL20289108 0.79 ALDH1A3 (0.30) ALDH1A3
SCHEMBL6790445 0.69 GAA (0.42) PTGER4
SCHEMBL27271318 0.68 POLB (0.35)
SCHEMBL24406092 0.67 S100B (0.35) ALDH1A3
SCHEMBL27931197 0.66 POLB (0.41) PTGER4
SCHEMBL18322618 0.66 PTGER4 (0.61) PTGER4
SCHEMBL239457 0.65 PTGER4 (0.43) PTGER4
SCHEMBL31387674 0.65 PTGER4 (0.43) PTGER4
SCHEMBL3836844 0.65 PTGER4 (0.43) PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782996-A1 NRF2 REGULATORS GlaxoSmithKline Intellectual Property Development Limited (GB) 2021-02-24 EP disclosed