SCHEMBL2301733

SCHEMBL2301733

O=C1OC2(c3ccccc3Oc3ccccc32)c2c(Nc3ccccc3)cccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.43
MEN1 O00255 6/20 0.43
KMT2A Q03164 6/20 0.43
HPGD P15428 6/20 0.43
FTO Q9C0B1 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
BLM P54132 2/20 0.43
HTT P42858 2/20 0.43
RECQL P46063 2/20 0.43
CYP2C19 P33261 1/20 0.43
SMAD3 P84022 1/20 0.43
PRMT1 Q99873 1/20 0.43
ACE2 Q9BYF1 1/20 0.43
CFTR P13569 1/20 0.42
GOPC Q9HD26 1/20 0.42
CYP3A4 P08684 4/20 0.38
ALDH1A1 P00352 7/20 0.38
LMNA P02545 5/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009769 0.92 MAPT (0.47) MAPTMEN1KMT2AHPGDFTO
SCHEMBL29967639 0.92 MAPT (0.47) MAPTMEN1KMT2AHPGDFTO
SCHEMBL10347645 0.84 FTO (0.44) MAPTMEN1KMT2AHPGDFTO
SCHEMBL3637742 0.84 MAPT (0.41) MAPTMEN1KMT2AHPGDFTO
SCHEMBL10636530 0.84 MAPT (0.41) MAPTMEN1KMT2AHPGDFTO
SCHEMBL10358541 0.83 MAPT (0.45) MAPTMEN1KMT2AHPGDFTO
SCHEMBL8505991 0.83 CYP2C19 (0.35) MAPTMEN1KMT2AHPGDFTO
SCHEMBL3346303 0.82 ALDH1A1 (0.40) MAPTMEN1KMT2AHPGDFTO
SCHEMBL10636960 0.82 LMNA (0.40) MAPTMEN1KMT2AHPGDFTO
SCHEMBL10637760 0.82 CYP3A4 (0.43) MAPTMEN1KMT2AHPGDFTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2349734-A1 AQUEOUS LASER-SENSITIVE COMPOSITION FOR MARKING SUBSTRATES DataLase Ltd (GB) 2011-08-03 EP claimed
WO-2010049281-A1 AQUEOUS LASER-SENSITIVE COMPOSITION FOR MARKING SUBSTRATES BASF SE (DE) 2010-05-06 WO claimed
EP-0610739-B1 Printed matter KAWASHIMA KIYOHARU (JP) 1997-07-30 EP claimed
EP-0161105-B1 RECORD MATERIAL APPLETON PAPERS INC. (US) 1989-12-20 EP claimed
EP-0100196-B1 THERMALLY RESPONSIVE RECORD MATERIAL APPLETON PAPERS INC. (US) 1986-07-30 EP claimed
EP-3758947-A1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER Solenis Technologies Cayman, L.P. (KY) 2021-01-06 EP disclosed
WO-2020054571-A1 INFORMATION RECORDING MEDIUM, ORIGINAL PLATE USED FOR PRODUCTION OF INFORMATION RECORDING MEDIUM, AND METHOD FOR PRODUCING INFORMATION RECORDING MEDIUM 大日本印刷株式会社 2020-03-19 WO disclosed
US-10202016-B2 Heat-sensitive recording material for offset printing MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2019-02-12 US disclosed
EP-3352991-A1 HEAT-SENSITIVE RECORDING MATERIAL Mitsubishi HiTec Paper Europe GmbH (DE) 2018-08-01 EP disclosed
US-20180001730-A1 Heat-Sensitive Recording Material For Offset Printing MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2018-01-04 US disclosed
CN-104797429-B Recording material using non-phenolic compound, recording sheet, and method for using non-phenolic compound for color developer 日本曹达株式会社 2017-04-19 CN disclosed
EP-1457345-B1 Thermal head printer and process for printing substantially light-insensitve recording materials. AGFA HEALTHCARE NV (BE) 2009-12-30 EP disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
EP-0083075-B1 COLOUR DEVELOPING SHEET FOR A PRESSURE-SENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1986-08-13 EP disclosed
EP-0100196-B1 THERMALLY RESPONSIVE RECORD MATERIAL APPLETON PAPERS INC. (US) 1986-07-30 EP disclosed
EP-0188377-A1 New phthalide derivatives KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1986-07-23 EP disclosed
EP-0059975-B1 THERMORESPONSIVE RECORDING SHEET Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-06-26 EP disclosed
EP-0029323-B1 USE OF VINYL PHENOL POLYMER AS COLOUR DEVELOPER FOR LEUCO PIGMENT AND COLOUR DEVELOPER COMPOSITION AND THERMOSENSITIVE RECORDING ELEMENT COMPRISING SAME MITA INDUSTRIAL CO. LTD. (JP) 1984-09-05 EP disclosed
EP-0058430-A1 Dyestuff-containing microscopic capsule dispersion for record materials MITSUI TOATSU CHEMICALS, Inc. (JP) 1982-08-25 EP disclosed
US-4273602-A Heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1981-06-16 US disclosed