Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142842 | 0.80 | ALDH1A1 (0.44) | KDM4EGAAALDH1A1HTTMAPT | |
| SCHEMBL19196836 | 0.79 | SMN1; SMN2 (0.49) | KDM4EMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL11144559 | 0.78 | LMNA (0.43) | KDM4EMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL11144562 | 0.78 | LMNA (0.43) | KDM4EMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL11114442 | 0.76 | ALDH1A1 (0.43) | KDM4EGAAALDH1A1HPGDMAPT | |
| SCHEMBL11153211 | 0.76 | ALDH1A1 (0.43) | KDM4EGAAALDH1A1HPGDMAPT | |
| SCHEMBL11114443 | 0.76 | ALDH1A1 (0.43) | KDM4EGAAALDH1A1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL11536173 | 0.75 | ALDH1A1 (0.42) | KDM4EGAAALDH1A1HPGDMAPT | |
| SCHEMBL19196768 | 0.75 | MEN1 (0.46) | KDM4EMEN1KMT2ASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL11536177 | 0.75 | ALDH1A1 (0.42) | KDM4EGAAALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177616-B1 | NOVEL ROUTES OF SYNTHESIS FOR THE PREPARATION OF SUVOREXANT | SANDOZ AG (CH) | 2021-02-24 | — | — | EP | disclosed |