Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.49 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23018477 | 0.86 | ALOX5 (0.53) | ALOX5TAOK1ABL1DRD2MAPT | |
| SCHEMBL18667587 | 0.85 | ALOX5 (0.45) | ALOX5TAOK1ABL1DRD2MAPT | |
| SCHEMBL18667885 | 0.83 | ALOX5 (0.43) | ALOX5TAOK1ABL1DRD2MAPT | |
| SCHEMBL23018498 | 0.83 | ALOX5 (0.43) | ALOX5TAOK1ABL1DRD2MAPT | |
| SCHEMBL18667892 | 0.81 | ALOX5 (0.43) | ALOX5TAOK1ABL1DRD2MAPT | |
| SCHEMBL18664524 | 0.79 | DRD2 (0.50) | ALOX5TAOK1ABL1DRD2ALDH1A1 | |
| SCHEMBL17086340 | 0.78 | ALOX5 (0.46) | ALOX5TAOK1ABL1DRD2ALDH1A1 | |
| SCHEMBL3593402 | 0.78 | ALOX5 (0.74) | ALOX5ABL1MAPTTP53SMN1; SMN2 | |
| SCHEMBL17086074 | 0.77 | ALOX5 (0.55) | ALOX5ABL1MAPTTP53ALDH1A1 | |
| SCHEMBL4748216 | 0.77 | ALOX5 (0.71) | ALOX5ABL1MAPTALDH1A1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782626-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Biosciences, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |