Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.53 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23018643 | 0.86 | ALOX5 (0.49) | ALOX5TAOK1ALDH1A1ABL1DRD2 | |
| SCHEMBL18664524 | 0.82 | DRD2 (0.50) | ALOX5TAOK1ALDH1A1ABL1DRD2 | |
| SCHEMBL18667587 | 0.82 | ALOX5 (0.45) | ALOX5TAOK1ALDH1A1ABL1DRD2 | |
| SCHEMBL17086340 | 0.82 | ALOX5 (0.46) | ALOX5TAOK1ALDH1A1ABL1DRD2 | |
| SCHEMBL3593402 | 0.81 | ALOX5 (0.74) | ALOX5ABL1SMN1; SMN2HTR7HTR2B | |
| SCHEMBL18667192 | 0.81 | ALOX5 (0.42) | ALOX5TAOK1ALDH1A1ABL1DRD2 | |
| SCHEMBL11221903 | 0.81 | ALOX5 (0.55) | ALOX5ALDH1A1ABL1SMN1; SMN2KDM4E | |
| SCHEMBL17086074 | 0.81 | ALOX5 (0.55) | ALOX5ALDH1A1ABL1HTR7HTR2B | |
| SCHEMBL4748216 | 0.81 | ALOX5 (0.71) | ALOX5ALDH1A1ABL1HTR7HTR2B | |
| SCHEMBL18381735 | 0.81 | ALOX5 (0.46) | ALOX5TAOK1ALDH1A1ABL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782626-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Biosciences, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |