Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19933523 | 0.91 | TRPV1 (0.60) | TRPV1BAZ2BPTPN1PTPN2P4HTM | |
| SCHEMBL18573397 | 0.85 | BAZ2B (0.68) | TRPV1BAZ2BPTPN1PTPN2P4HTM | |
| SCHEMBL22563324 | 0.84 | TRPV1 (0.53) | TRPV1BAZ2BPTPN1PTPN2P4HTM | |
| SCHEMBL23018724 | 0.81 | HPGDS (0.53) | TRPV1BAZ2BPTPN1PTPN2P4HTM | |
| SCHEMBL1543044 | 0.80 | PTPN1 (0.70) | TRPV1BAZ2BPTPN1PTPN2P4HTM | |
| SCHEMBL19933601 | 0.79 | PTPN1 (0.68) | TRPV1BAZ2BPTPN1PTPN2P4HTM | |
| SCHEMBL20006909 | 0.78 | TRPV1 (0.47) | TRPV1BAZ2BPTPN1PTPN2P4HTM | |
| SCHEMBL5934176 | 0.77 | DHODH (0.50) | P4HTMKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL5934432 | 0.76 | MAPT (0.63) | TRPV1BAZ2BPTPN1PTPN2HPGDS | |
| SCHEMBL5934037 | 0.75 | WNT3A (0.51) | P4HTMKDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507294-B1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | disclosed |