Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452035 | 0.95 | PLA2G2A (0.35) | MMP12MMP13GAAL3MBTL1PTPN2 | |
| SCHEMBL27451692 | 0.94 | MMP12 (0.34) | MMP12MMP13GAAL3MBTL1PTPN2 | |
| SCHEMBL21755956 | 0.91 | MMP12 (0.34) | MMP12MMP13GAAL3MBTL1AHR | |
| SCHEMBL26155965 | 0.90 | RAB9A (0.37) | MMP12MMP13GAAAHRPLA2G2A | |
| SCHEMBL27451388 | 0.90 | PLA2G2A (0.36) | GAAL3MBTL1PTPN2PTPN1PRKDC | |
| SCHEMBL17612085 | 0.89 | MMP12 (0.36) | MMP12MMP13GAAL3MBTL1AHR | |
| SCHEMBL21926223 | 0.89 | MAPT (0.35) | MMP12MMP13AHRKDM4EALDH1A1 | |
| SCHEMBL21968791 | 0.88 | AHR (0.41) | GAAAHRKDM4EALDH1A1HPGD | |
| SCHEMBL21755961 | 0.88 | HSP90AA1 (0.35) | MMP12MMP13GAAL3MBTL1AHR | |
| SCHEMBL23098282 | 0.87 | KMT2A (0.32) | L3MBTL1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507294-B1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | disclosed |