SCHEMBL2302131

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28011915	0.84	CA12 (0.64)	CES2CFTRCA12CA1CA2
	SCHEMBL284138	0.82	CFTR (0.64)	CES2CFTRGAAKDM4EUSP2
	SCHEMBL14213133	0.80	ALDH1A1 (0.52)	CA12CA1CA2CA7CA9
	SCHEMBL15255299	0.80	CES2 (0.55)	CES2CA12CA1CA2CA7
	SCHEMBL27961391	0.80	CFTR (0.47)	CES2CFTRCA12CA1CA2
	SCHEMBL2073688	0.80	CES2 (0.52)	CES2CFTRPDE2AGAAKDM4E
	SCHEMBL29786688	0.80	CES2 (0.52)	CES2CFTRPDE2AGAAKDM4E
	SCHEMBL955971	0.79	KDM4E (0.48)	CES2CFTRCA12CA1CA2
	SCHEMBL7249540	0.79	CFTR (0.46)	CES2CFTRCA12CA1CA2
	SCHEMBL12780275	0.79	PDE2A (0.47)	CES2CFTRPDE2AGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.