Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023591 | 0.86 | PTGS2 (0.40) | PTGS2TSHRMBNL1LMNASMN1; SMN2 | |
| SCHEMBL25150557 | 0.84 | KDM5B (0.40) | PTGS2TSHRMBNL1LMNASMN1; SMN2 | |
| SCHEMBL23023564 | 0.82 | DHODH (0.40) | PTGS2TSHRKCNQ3KCNQ2DHODH | |
| SCHEMBL29703817 | 0.77 | JAK2 (0.47) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23013510 | 0.77 | JAK2 (0.47) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23023602 | 0.72 | HTR6 (0.41) | PTGS2MBNL1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL16646633 | 0.69 | MAPT (0.44) | PTGS2LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25742238 | 0.66 | PTGS2 (0.41) | PTGS2SMN1; SMN2MAPTMAOBMAOA | |
| SCHEMBL21490283 | 0.66 | SCN9A (0.45) | LMNA | |
| SCHEMBL10091158 | 0.66 | NPC1 (0.44) | MBNL1SMN1; SMN2ALDH1A1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032992-A1 | PHARMACEUTICAL COMPOUNDS | ReViral Limited (GB) | 2021-02-25 | — | — | WO | disclosed |