Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023571 | 0.86 | ADORA2A (0.40) | HTR6PTGS2MBNL1ADORA2AADORA1 | |
| SCHEMBL25150574 | 0.83 | PTGS2 (0.38) | HTR6PTGS2MBNL1ADORA2AADORA1 | |
| SCHEMBL23023590 | 0.83 | PTGS2 (0.44) | HTR6PTGS2ADORA2AADORA1ADORA2B | |
| SCHEMBL29703800 | 0.81 | DHODH (0.41) | HTR6PTGS2MBNL1ADORA2AADORA1 | |
| SCHEMBL23013548 | 0.81 | DHODH (0.41) | HTR6PTGS2MBNL1ADORA2AADORA1 | |
| SCHEMBL29703797 | 0.77 | ALDH1A1 (0.44) | NPC1MAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL23013511 | 0.77 | ALDH1A1 (0.44) | NPC1MAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL23023710 | 0.72 | PTGS2 (0.42) | PTGS2MBNL1NPC1MAPTTP53 | |
| SCHEMBL23047161 | 0.70 | PDE10A (0.44) | HTR6PTGS2NPC1PDE10AMAPT | |
| SCHEMBL23998550 | 0.69 | ADORA2A (0.35) | MBNL1ADORA2AADORA1ADORA2BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032992-A1 | PHARMACEUTICAL COMPOUNDS | ReViral Limited (GB) | 2021-02-25 | — | — | WO | disclosed |