SCHEMBL230240

SCHEMBL230240

O=C1CCC(=O)N1C(O)(C(=O)O)C(O)(C(=O)O)N1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16875688 1.00 CA12 (0.33) CA12CA1CA9
SCHEMBL721353 0.76 CA12 (0.31) CA12CA1CA9
SCHEMBL1010019 0.76 CA12 (0.35) CA12CA1CA9
SCHEMBL7209074 0.75 POLB (0.35) CA12CA1CA9
SCHEMBL913291 0.73 POLB (0.34) CA12CA1CA9
SCHEMBL29876297 0.73 CA12 (0.36) CA12CA1CA9
SCHEMBL1350795 0.73 PARL (0.31)
SCHEMBL3143318 0.72
SCHEMBL4001225 0.72 MAPT (0.35)
SCHEMBL23781544 0.70 CPT2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2971064-B1 PROXIMITY ASSAY FOR IN SITU DETECTION OF TARGETS VENTANA MED SYST INC (US) 2019-10-16 EP claimed
EP-2282758-B1 ANTIBODIES AND VACCINES FOR USE IN THERAPEUTIC AND DIAGNOSTIC METHODS FOR ALPHA-SYNUCLEIN-RELATED DISORDERS BIOARCTIC AB (SE) 2018-11-21 EP claimed
EP-3171171-B1 RECOMBINANT DEAMIDATED GLIADIN ANTIGEN BIO RAD LABORATORIES (US) 2018-07-18 EP claimed
EP-3010534-B1 PHARMACEUTICAL FORMULATIONS AND METHODS FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE INGREDIENT TRANSGENE BIOTEK TLD (IN) 2018-05-30 EP claimed
EP-2494075-B1 TEMPLATED NANOCONJUGATES UNIV NORTHWESTERN (US) 2018-04-04 EP claimed
US-9663814-B2 Proximity assay for in situ detection of targets VENTANA MEDICAL SYSTEMS, INC. (US) 2017-05-30 US claimed
EP-2788760-B1 RECOMBINANT DEAMIDATED GLIADIN ANTIGEN BIO RAD LABORATORIES INC (US) 2017-02-15 EP claimed
EP-1853634-B1 ACTIVATED SIALIC ACID DERIVATIVES FOR PROTEIN DERIVATISATION AND CONJUGATION LIPOXEN TECHNOLOGIES LTD (GB) 2016-08-10 EP claimed
EP-1776389-B1 SIALIC ACID DERIVATIVES LIPOXEN TECHNOLOGIES LTD (GB) 2016-06-29 EP claimed
EP-2971064-A1 PROXIMITY ASSAY FOR IN SITU DETECTION OF TARGETS Ventana Medical Systems, Inc. (US) 2016-01-20 EP claimed
EP-2276499-B1 RECOMBINANT DEAMIDATED GLIADIN ANTIGEN BIO RAD LABORATORIES (US) 2013-06-12 EP claimed
EP-2126584-B1 DIRECT MASS SPECTROMETRIC ANALYSIS OF DRUG CANDIDATES TARGETING PROTEIN COMPLEXES COVALX AG (CH) 2012-12-19 EP claimed
EP-2408470-A1 Soluble non-depot insulin conjugates and uses thereof Smartcells, Inc. (US) 2012-01-25 EP claimed
EP-2095129-B1 DIRECT MASS SPECTROMETRIC ANALYSIS OF SELF-AGGREGATES OF THERAPEUTIC PROTEINS COVALX AG (SE) 2011-02-23 EP claimed
WO-2010107520-A1 SOLUBLE NON-DEPOT INSULIN CONJUGATES AND USES THEREOF SMARTCELLS, INC. (US) 2010-09-23 WO claimed
EP-0701448-B1 AMPLIFICATION OF THE VITAMIN B 12 UPTAKE SYSTEM USING POLYMERS BIOTECH AUSTRALIA PTY LTD (AU) 2002-08-14 EP claimed
US-5427929-A Enzyme pretreatment AMGEN INC. (US) 1995-06-27 US claimed
EP-0220030-B1 ORAL DELIVERY SYSTEM BIOTECHNOLOGY AUSTRALIA PTY. LTD. (AU) 1991-06-19 EP claimed
WO-1988008875-A1 CYCLING BIOCHIP SENSOR THE WASHINGTON TECHNOLOGY CENTER (US) 1988-11-17 WO claimed
EP-0184710-A2 Magnetic microspheres BAYER AG (DE) 1986-06-18 EP claimed