Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230240 | 0.76 | CA12 (0.33) | CA12CA1CA9 | |
| SCHEMBL16875688 | 0.76 | CA12 (0.33) | CA12CA1CA9 | |
| SCHEMBL1010019 | 0.73 | CA12 (0.35) | CA12CA1CA9 | |
| SCHEMBL7209074 | 0.71 | POLB (0.35) | CA12CA1CA9 | |
| SCHEMBL29876297 | 0.70 | CA12 (0.36) | CA12CA1CA9 | |
| SCHEMBL913291 | 0.70 | POLB (0.34) | CA12CA1CA9 | |
| SCHEMBL43721 | 0.70 | POLB (0.32) | — | |
| SCHEMBL4001225 | 0.68 | MAPT (0.35) | — | |
| SCHEMBL23781544 | 0.67 | CPT2 (0.34) | — | |
| SCHEMBL25217270 | 0.67 | LMNA (0.32) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313447-A2 | COMPOSITIONS FOR DELIVERY TO AND TREATMENT OF ATHEROSCLEROTIC PLAQUES | Sanford Burnham Prebys Medical Discovery Institute (US) | 2018-05-02 | — | — | EP | disclosed |
| WO-2017040976-A1 | COMPOUNDS AND COMPOSITIONS FOR TARGETING BRAIN INJURIES AND METHODS OF USE THEREOF | RUOSLAHTI ERKKI (US) | 2017-03-09 | — | — | WO | disclosed |
| WO-2016210423-A9 | COMPOSITIONS FOR DELIVERY TO AND TREATMENT OF ATHEROSCLEROTIC PLAQUES | Sanford Burnham Prebys Medical Discovery Institute (US) | 2017-02-02 | — | — | WO | disclosed |
| WO-2016210423-A2 | COMPOSITIONS FOR DELIVERY TO AND TREATMENT OF ATHEROSCLEROTIC PLAQUES | Sanford Burnham Prebys Medical Discovery Institute (US) | 2016-12-29 | — | — | WO | disclosed |
| WO-2016172515-A1 | TARGETED DELIVERY SYSTEM AND METHODS OF USE THEREFOR | Sanford Burnham Prebys Medical Discovery Institute (US) | 2016-10-27 | — | — | WO | disclosed |
| WO-2014201118-A2 | COMPOSITIONS AND METHODS FOR TARGETED ENDOMETRIOSIS TREATMENT | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2014-12-18 | — | — | WO | disclosed |
| EP-2709664-A1 | BLOCKADE OF TL1A-DR3 INTERACTIONS TO AMELIORATE T CELL MEDIATED DISEASE PATHOLOGY AND ANTIBODIES THEREOF | The Government of the United States, as represented by The Secretary of the Department of Health and Human Services (US) | 2014-03-26 | — | — | EP | disclosed |
| EP-2555802-A1 | METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF COMPOUNDS | Sanford-Burnham Medical Research Institute (US) | 2013-02-13 | — | — | EP | disclosed |
| WO-2013019745-A1 | METHODS AND COMPOSITIONS FOR GENETICALLY MODIFIYING CELLS | Georgia Health Sciences University (US) | 2013-02-07 | — | — | WO | disclosed |
| WO-2012161856-A1 | BLOCKADE OF TL1A-DR3 INTERACTIONS TO AMELIORATE T CELL MEDIATED DISEASE PATHOLOGY AND ANTIBODIES THEREOF | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-11-29 | — | — | WO | disclosed |
| WO-2009100218-A2 | KRUPPEL-LIKE TRANSCRIPTION FACTOR KLF4/GKLF AND USES THEREOF | UAB RESEARCH FOUNDATION (US) | 2009-08-13 | — | — | WO | disclosed |
| EP-1996607-A4 | LYMPHATIC ZIP CODES IN TUMORS AND PRE-MALIGNANT LESIONS | BURNHAM INST MEDICAL RESEARCH (US) | 2009-06-24 | — | — | EP | disclosed |
| WO-2009023306-A2 | TARGETING HOST PROTEINASES AS A THERAPEUTIC STRATEGY AGAINST VIRAL AND BACTERIAL PATHOGENS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009017863-A2 | TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE INHIBITORS AND USES THEREOF FOR TREATING VASCULAR CALCIFICATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009018429-A2 | TREATMENT OF CANCER VIA TARGETING OF IL-13 RECEPTOR-α2 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, ASREPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALT OF HUMAN SERVICES, NATIONAL INSTITUTES OF HEALT (US) | 2009-02-05 | — | — | WO | disclosed |
| EP-1996607-A2 | LYMPHATIC ZIP CODES IN TUMORS AND PRE-MALIGNANT LESIONS | The Burnham Institute for Medical Research (US) | 2008-12-03 | — | — | EP | disclosed |
| EP-1966234-A2 | ENDOMETRIOSIS CELL TARGETING PEPTIDES AND USES THEREOF | The Burnham Institute for Medical Research (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2008054726-A2 | TARGETING NBS1-ATM INTERACTION TO SENSITIZE CANCER CELLS TO RADIOTHERAPY AND CHEMOTHERAPY | SOUTHERN RESEARCH INSTITUTE (US) | 2008-05-08 | — | — | WO | disclosed |
| WO-2007090194-A2 | LYMPHATIC ZIP CODES IN TUMORS AND PRE-MALIGNANT LESIONS | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2007-08-09 | — | — | WO | disclosed |
| WO-2007076501-A2 | ENDOMETRIOSIS CELL TARGETING PEPTIDE AND USES THEREOF | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2007-07-05 | — | — | WO | disclosed |