Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876297 | 0.79 | CA12 (0.36) | CA12CA1CA9ALDH1A1PKM | |
| SCHEMBL230240 | 0.76 | CA12 (0.33) | CA12CA1CA9 | |
| SCHEMBL16875688 | 0.76 | CA12 (0.33) | CA12CA1CA9 | |
| SCHEMBL3132415 | 0.76 | CA12 (0.34) | CA12CA1CA9ALDH1A1PKM | |
| SCHEMBL721353 | 0.73 | CA12 (0.31) | CA12CA1CA9 | |
| SCHEMBL6675625 | 0.72 | CA12 (0.32) | CA12CA1CA9ALDH1A1PKM | |
| SCHEMBL5156474 | 0.71 | CA12 (0.32) | CA12CA1CA9ALDH1A1PKM | |
| SCHEMBL5156471 | 0.71 | ALDH1A1 (0.34) | CA12CA1CA9ALDH1A1PKM | |
| SCHEMBL913291 | 0.70 | POLB (0.34) | CA12CA1CA9ALDH1A1 | |
| SCHEMBL9499912 | 0.69 | CA12 (0.30) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313447-A2 | COMPOSITIONS FOR DELIVERY TO AND TREATMENT OF ATHEROSCLEROTIC PLAQUES | Sanford Burnham Prebys Medical Discovery Institute (US) | 2018-05-02 | — | — | EP | disclosed |
| WO-2017040976-A1 | COMPOUNDS AND COMPOSITIONS FOR TARGETING BRAIN INJURIES AND METHODS OF USE THEREOF | RUOSLAHTI ERKKI (US) | 2017-03-09 | — | — | WO | disclosed |
| WO-2016210423-A9 | COMPOSITIONS FOR DELIVERY TO AND TREATMENT OF ATHEROSCLEROTIC PLAQUES | Sanford Burnham Prebys Medical Discovery Institute (US) | 2017-02-02 | — | — | WO | disclosed |
| WO-2016210423-A2 | COMPOSITIONS FOR DELIVERY TO AND TREATMENT OF ATHEROSCLEROTIC PLAQUES | Sanford Burnham Prebys Medical Discovery Institute (US) | 2016-12-29 | — | — | WO | disclosed |
| WO-2016172515-A1 | TARGETED DELIVERY SYSTEM AND METHODS OF USE THEREFOR | Sanford Burnham Prebys Medical Discovery Institute (US) | 2016-10-27 | — | — | WO | disclosed |
| WO-2014201118-A2 | COMPOSITIONS AND METHODS FOR TARGETED ENDOMETRIOSIS TREATMENT | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2014-12-18 | — | — | WO | disclosed |
| WO-2013019745-A1 | METHODS AND COMPOSITIONS FOR GENETICALLY MODIFIYING CELLS | Georgia Health Sciences University (US) | 2013-02-07 | — | — | WO | disclosed |
| WO-2011143111-A1 | ENDOTHELIAL NITRIC OXIDE SYNTHASE ANTAGONISTS AND USES THEREOF FOR INHIBITING OXYGEN TOXICITY | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011022103-A2 | GANGLIOSIDE EPITOPES FOR TREATING GUILLAIN-BARRE SYNDROME | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2011-02-24 | — | — | WO | disclosed |
| WO-2011006069-A1 | PEPTIDES FOR BINDING FIBRINOGEN AND FIBRIN | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | WO | disclosed |
| EP-2268664-A2 | DOC1 COMPOSITIONS AND METHODS FOR TREATING CANCER | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2011-01-05 | — | — | EP | disclosed |
| WO-2010070380-A2 | DOC1 COMPOSITIONS AND METHODS FOR TREATING CANCER | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH OF HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) | 2010-06-24 | — | — | WO | disclosed |
| EP-1966234-A2 | ENDOMETRIOSIS CELL TARGETING PEPTIDES AND USES THEREOF | The Burnham Institute for Medical Research (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007076501-A2 | ENDOMETRIOSIS CELL TARGETING PEPTIDE AND USES THEREOF | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-1995018971-A1 | METHODS FOR THE SOLID PHASE SYNTHESIS OF GLYCOCONJUGATES | AFFYMAX TECHNOLOGIES N.V. (NL) | 1995-07-13 | — | — | WO | disclosed |