Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 7/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23025142 | 0.90 | ACLY (0.35) | ACLYPTGDR2MEN1MAPTKMT2A | |
| SCHEMBL20233095 | 0.78 | THRB (0.34) | ACLY | |
| SCHEMBL17069252 | 0.77 | HTR2A (0.33) | MAOB | |
| SCHEMBL17061815 | 0.76 | PNMT (0.32) | MAOBIDO1 | |
| SCHEMBL29738536 | 0.76 | PNMT (0.32) | MAOBIDO1 | |
| SCHEMBL22889496 | 0.76 | IDO1 (0.42) | PTGDR2MAPTIDO1 | |
| SCHEMBL16960654 | 0.76 | PTGDR2 (0.43) | MAOBPTGDR2P2RX7MEN1MAPT | |
| SCHEMBL13755087 | 0.74 | IDO1 (0.34) | ACLYMEN1KMT2ACRHR1IDO1 | |
| SCHEMBL10835146 | 0.74 | PNMT (0.31) | — | |
| SCHEMBL21807098 | 0.73 | HSP90AB1 (0.51) | MAOBACLYMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032582-A1 | PYRAZOLO[4,3-C]PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | GALAPAGOS NV (BE) | 2021-02-25 | — | — | WO | disclosed |