Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125733 | 0.92 | ENPP1 (0.40) | CA12CA9CA1CA2ENPP1 | |
| SCHEMBL126767 | 0.92 | ENPP1 (0.40) | CA12CA9CA1CA2ENPP1 | |
| SCHEMBL17934708 | 0.89 | ENPP1 (0.45) | CA12CA9CA1CA2ENPP1 | |
| SCHEMBL13697088 | 0.88 | CA12 (0.41) | CA12CA9CA1CA2ENPP1 | |
| SCHEMBL13995115 | 0.88 | ENPP1 (0.42) | CA12CA9CA1CA2ENPP1 | |
| SCHEMBL126429 | 0.87 | ALDH1A1 (0.40) | CA12CA9CA1CA2ENPP1 | |
| SCHEMBL17935585 | 0.87 | ALDH1A1 (0.40) | CA12CA9CA1CA2ENPP1 | |
| SCHEMBL126261 | 0.87 | ALDH1A1 (0.40) | CA12CA9CA1CA2ENPP1 | |
| SCHEMBL13995089 | 0.86 | HSD17B1 (0.37) | CA12CA9CA1CA2SLC6A9 | |
| SCHEMBL23027127 | 0.86 | ESR1 (0.39) | KDM4EALDH1A1HSD17B10TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365167-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-06-21 | — | — | US | disclosed |
| US-20210053894-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053894-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | CA12 1065/4885CA9 1527/4885CA1 1105/4885 |
| US-11365167-B2 | Materials for organic electroluminescent devices | L1CAM, EFNA1, EPCAM | CA12 1065/4885CA9 1527/4885CA1 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.