Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23027450 | 0.79 | HTR1A (0.36) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL31566428 | 0.72 | KDM4E (0.35) | — | |
| SCHEMBL31474160 | 0.71 | S1PR5 (0.34) | — | |
| SCHEMBL31304822 | 0.71 | HTR1A (0.31) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL31359428 | 0.70 | HTR1A (0.38) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL20994824 | 0.69 | — | — | |
| SCHEMBL30486608 | 0.65 | EGFR (0.33) | — | |
| SCHEMBL25346478 | 0.65 | EGFR (0.33) | — | |
| SCHEMBL31310143 | 0.64 | BACE1 (0.32) | — | |
| SCHEMBL31482950 | 0.64 | ADRA2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841803-A | Amide substituted heteroaryl compounds, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-04-18 | — | — | CN | disclosed |