Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23027466 | 0.79 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MAPTFFAR4LMNA | |
| SCHEMBL21955264 | 0.76 | EZH2 (0.33) | ALDH1A1SMN1; SMN2EZH2 | |
| SCHEMBL17535618 | 0.75 | EZH2 (0.32) | ALDH1A1SMN1; SMN2EZH2NFE2L2 | |
| SCHEMBL3451196 | 0.74 | KDM4E (0.42) | ALDH1A1MAPTFFAR4LMNACYP1A2 | |
| SCHEMBL8388701 | 0.73 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2EZH2 | |
| SCHEMBL30813517 | 0.71 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9928247 | 0.71 | CETP (0.33) | ALDH1A1SMN1; SMN2MAPTEZH2LMNA | |
| SCHEMBL21954934 | 0.71 | EZH2 (0.39) | ALDH1A1SMN1; SMN2MAPTEZH2LMNA | |
| SCHEMBL31085082 | 0.69 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL25317647 | 0.68 | TRPV4 (0.33) | ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032074-A1 | BENZAMIDE FUSED AROMATIC RING DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2021-02-25 | — | — | WO | disclosed |