Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17535572 | 0.85 | EZH2 (0.34) | EZH2 | |
| SCHEMBL23027467 | 0.76 | ALDH1A1 (0.34) | EZH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL21955373 | 0.75 | NOS3 (0.36) | EZH2ALDH1A1 | |
| SCHEMBL21955372 | 0.75 | NOS3 (0.36) | EZH2ALDH1A1 | |
| SCHEMBL17535618 | 0.72 | EZH2 (0.32) | EZH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL21955174 | 0.72 | — | — | |
| SCHEMBL3451196 | 0.71 | KDM4E (0.42) | ALDH1A1 | |
| SCHEMBL8388701 | 0.70 | ALDH1A1 (0.32) | EZH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30813517 | 0.69 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9928247 | 0.69 | CETP (0.33) | EZH2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996786-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-08-20 | — | — | CN | disclosed |
| US-20220226337-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | GILEAD SCIENCES, INC. | 2022-07-21 | — | — | US | disclosed |
| US-11224600-B2 | Compounds for inhibition of alpha 4 beta 7 integrin | GILEAD SCIENCES, INC. (US) | 2022-01-18 | — | — | US | disclosed |
| EP-3873897-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | GILEAD SCIENCES, INC. (US) | 2021-09-08 | — | — | EP | disclosed |
| CN-112996786-A | Compounds for inhibiting alpha 4 beta 7 integrins | 吉利德科学公司 | 2021-06-18 | — | — | CN | disclosed |
| US-20200155563-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | GILEAD SCIENCES, INC. | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220226337-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | ITGB7, ITGB4, ITGA4 | EZH2 2843/4885ALDH1A1 823/4885SMN1; SMN2 1977/4885 |
| US-20200155563-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | ITGB7, ITGB4, ITGA4 | EZH2 2843/4885ALDH1A1 823/4885SMN1; SMN2 1977/4885 |
| US-11224600-B2 | Compounds for inhibition of alpha 4 beta 7 integrin | ITGB7, ITGB4, ITGA4 | EZH2 2843/4885ALDH1A1 823/4885SMN1; SMN2 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.