Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508456 | 1.00 | NR4A2 (0.37) | NR4A2F7F3LMNANPSR1 | |
| SCHEMBL23013176 | 0.94 | F7 (0.36) | NR4A2F7F3LMNANPSR1 | |
| SCHEMBL29733568 | 0.82 | — | — | |
| SCHEMBL3918289 | 0.77 | GABRA1 (0.54) | NR4A2F7F3MEN1KMT2A | |
| SCHEMBL29508438 | 0.74 | MAOA (0.46) | NR4A2F7F3NPSR1MAPT | |
| SCHEMBL23028621 | 0.74 | MAOA (0.46) | NR4A2F7F3NPSR1MAPT | |
| SCHEMBL29948545 | 0.73 | NPC1 (0.40) | LMNAMEN1KMT2AMT-CO2RAB9A | |
| SCHEMBL13389990 | 0.73 | TRPM8 (0.37) | MEN1MAPTKMT2ARAB9A | |
| SCHEMBL7220652 | 0.72 | NR4A2 (0.36) | NR4A2F7F3LMNAMEN1 | |
| SCHEMBL19463917 | 0.71 | MAOA (0.46) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032934-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-25 | — | — | WO | disclosed |