Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23028563 | 0.88 | — | — | |
| SCHEMBL23028569 | 0.82 | TDP1 (0.32) | TDP1APP | |
| SCHEMBL23028566 | 0.80 | — | — | |
| SCHEMBL23028650 | 0.80 | POLB (0.30) | POLB | |
| SCHEMBL23028652 | 0.76 | ALDH1A1 (0.31) | TDP1ALDH1A1POLB | |
| SCHEMBL23028560 | 0.73 | CES1 (0.36) | CES1NCEH1 | |
| SCHEMBL23028559 | 0.73 | TSHR (0.47) | ALDH1A1TSHRSMN1; SMN2L3MBTL1CES1 | |
| SCHEMBL7594598 | 0.72 | TDP1 (0.48) | TDP1ALDH1A1POLBTSHRSMN1; SMN2 | |
| SCHEMBL15333044 | 0.70 | RXRA (0.41) | ALDH1A1TSHRCES1NCEH1 | |
| SCHEMBL28118444 | 0.67 | TDP1 (0.72) | TDP1ALDH1A1TSHRSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034548-A1 | MITOCHONDRIAL MODULATION TO IMPROVE METABOLIC SYNDROME DURING AGING | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | WO | disclosed |