Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588536 | 0.92 | TDP1 (0.43) | TDP1CYP1A2DGKAADRA2AADRA1A | |
| SCHEMBL10523871 | 0.92 | TDP1 (0.43) | TDP1CYP1A2DGKAADRA2AADRA1A | |
| SCHEMBL7600473 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL9420467 | 0.90 | TDP1 (0.42) | TDP1CYP1A2DGKAADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL11853747 | 0.89 | MAPT (0.44) | TDP1CYP1A2DGKAADRA2AADRA1A | |
| SCHEMBL2568519 | 0.88 | TSHR (0.44) | TDP1CYP1A2DGKAADRA2AADRA1A | |
| SCHEMBL4381200 | 0.88 | ALDH1A1 (0.46) | TDP1CYP1A2DGKAADRA2AADRA1A | |
| SCHEMBL5378203 | 0.87 | — | — | |
| SCHEMBL8923707 | 0.85 | — | — | |
| SCHEMBL3893367 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002053526-A1 | NEW COMPOUNDS FOR USE AS INTERMEDIATES IN LINEAR BLOCK POLYMER AND NEW LINEAR BLOCK POLYMER | ARTIMPLANT AB (SE) | 2002-07-11 | — | — | WO | claimed |
| WO-2002053616-A1 | NEW LINEAR BLOCK POLYMER | ARTIMPLANT AB (SE) | 2002-07-11 | — | — | WO | claimed |
| WO-2002053526-A1 | NEW COMPOUNDS FOR USE AS INTERMEDIATES IN LINEAR BLOCK POLYMER AND NEW LINEAR BLOCK POLYMER | ARTIMPLANT AB (SE) | 2002-07-11 | — | — | WO | disclosed |
| WO-2002053616-A1 | NEW LINEAR BLOCK POLYMER | ARTIMPLANT AB (SE) | 2002-07-11 | — | — | WO | disclosed |