Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.47 |
| ▸ | CDK9 | P50750 | 3/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 3/20 | 0.45 |
| ▸ | USP1 | O94782 | 1/20 | 0.44 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17700718 | 0.88 | CRHR1 (0.51) | USP30CRHR1NPSR1HSD17B10NPC1 | |
| SCHEMBL29508428 | 0.81 | EGLN2 (0.47) | CCNT1CDK9USP30PIM1KCNH2 | |
| SCHEMBL23013075 | 0.81 | EGLN2 (0.47) | CCNT1CDK9USP30PIM1KCNH2 | |
| SCHEMBL23013101 | 0.80 | KDM4E (0.47) | CCNT1CDK9USP30PIM1KCNH2 | |
| SCHEMBL29508430 | 0.80 | KDM4E (0.47) | CCNT1CDK9USP30PIM1KCNH2 | |
| SCHEMBL13118523 | 0.79 | GRIN2B (0.57) | CCNT1CDK9USP30USP1WDR48 | |
| SCHEMBL26268478 | 0.77 | OPRM1 (0.51) | CCNT1PIM1HTR3EHTR3BHTR3A | |
| SCHEMBL1441523 | 0.76 | NPSR1 (0.43) | CCNT1CRHR1NPSR1HSD17B10NPC1 | |
| SCHEMBL1441524 | 0.76 | NPSR1 (0.43) | CCNT1CRHR1NPSR1HSD17B10NPC1 | |
| SCHEMBL24151174 | 0.74 | P2RX7 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032934-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-25 | — | — | WO | disclosed |