Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21142262 | 0.95 | BDKRB2 (0.40) | BDKRB2ALDH1A1HTTRIPK1GCGR | |
| SCHEMBL23030534 | 0.82 | HTT (0.35) | ALDH1A1HTTRIPK1DPP4MAPT | |
| SCHEMBL13003497 | 0.81 | S1PR1 (0.37) | BDKRB2HTTPTGESALOX5PPARG | |
| SCHEMBL15736896 | 0.80 | BDKRB2 (0.52) | BDKRB2ALDH1A1MAOAMAOBMME | |
| SCHEMBL8036329 | 0.80 | BDKRB2 (0.37) | BDKRB2ALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL13003489 | 0.76 | BDKRB2 (0.42) | BDKRB2ALDH1A1MAOAMAOB | |
| SCHEMBL23095177 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HTTRIPK1ALOX5PPARG | |
| SCHEMBL14402462 | 0.75 | RIPK1 (0.38) | ALDH1A1HTTRIPK1DPP4MAOA | |
| SCHEMBL13849936 | 0.75 | RIPK1 (0.38) | ALDH1A1HTTRIPK1DPP4MAOA | |
| SCHEMBL19121747 | 0.75 | SKP2 (0.50) | ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032933-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-25 | — | — | WO | disclosed |