Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23031868 | 0.81 | IDO1 (0.42) | RAB9ANPC1SMN1; SMN2IDO1MAOB | |
| SCHEMBL23031872 | 0.79 | LOXL2 (0.43) | RAB9ANPC1SMN1; SMN2GAAIDO1 | |
| SCHEMBL23031999 | 0.78 | RAB9A (0.34) | RAB9ANPC1SMN1; SMN2GAAIDO1 | |
| SCHEMBL23031850 | 0.73 | KDM4E (0.35) | MAPT | |
| SCHEMBL3401155 | 0.72 | LOXL2 (0.56) | RAB9ANPC1SMN1; SMN2GAAIDO1 | |
| SCHEMBL3722688 | 0.70 | HTT (0.51) | RAB9ANPC1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL19002292 | 0.69 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2GAALOXL2 | |
| SCHEMBL28887579 | 0.69 | LOXL2 (0.59) | RAB9ANPC1SMN1; SMN2GAAIDO1 | |
| SCHEMBL31224597 | 0.68 | LOXL2 (0.52) | RAB9ANPC1SMN1; SMN2GAAIDO1 | |
| SCHEMBL17855825 | 0.67 | MMP3 (0.56) | RAB9ANPC1SMN1; SMN2GAALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034924-A1 | TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS | BIOGEN MA INC. (US) | 2021-02-25 | — | — | WO | disclosed |