Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157078 | 0.79 | ERCC1 (0.50) | EPHX2NR1H4HDAC1KDM4ETP53 | |
| SCHEMBL24779944 | 0.77 | HPGD (0.59) | RIPK1HPGDSMN1; SMN2 | |
| SCHEMBL12103897 | 0.77 | KMT2A (0.56) | HDAC6EPHX2NR1H4HDAC1KDM4E | |
| SCHEMBL16616006 | 0.75 | NAMPT (0.53) | HDAC6EPHX2NR1H4CA1CA2 | |
| SCHEMBL23031847 | 0.75 | HPGD (0.45) | HDAC6CA1CA2HPGDKDM4E | |
| SCHEMBL25511293 | 0.74 | KMT2A (0.41) | HDAC6EPHX2NR1H4HPGDHDAC1 | |
| SCHEMBL15748044 | 0.72 | CYP3A4 (0.55) | HDAC6EPHX2HPGDHDAC1KDM4E | |
| SCHEMBL22009219 | 0.72 | TSHR (0.39) | HDAC6HPGDHDAC1SMN1; SMN2HDAC3 | |
| SCHEMBL21422726 | 0.72 | TPSAB1 (0.46) | HDAC6EPHX2HPGDHDAC1HDAC3 | |
| SCHEMBL17803834 | 0.72 | TPSAB1 (0.46) | HDAC6EPHX2NR1H4HPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034924-A1 | TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS | BIOGEN MA INC. (US) | 2021-02-25 | — | — | WO | disclosed |