Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21151955 | 0.85 | ERCC1 (0.50) | ERCC1ERCC4HDAC1KMT2ALMNA | |
| SCHEMBL12103897 | 0.83 | KMT2A (0.56) | HDAC1KMT2AMAPTKDM4ETP53 | |
| SCHEMBL24558042 | 0.82 | ERCC1 (0.64) | ERCC1ERCC4HDAC1KMT2ALMNA | |
| SCHEMBL25511293 | 0.81 | KMT2A (0.41) | HDAC1KMT2AMAPTKDM4ETP53 | |
| SCHEMBL12131750 | 0.80 | ERCC1 (0.70) | ERCC1ERCC4HDAC1KMT2ALMNA | |
| SCHEMBL21422726 | 0.80 | TPSAB1 (0.46) | HDAC1KMT2ALMNAEPHX2ALDH1A1 | |
| SCHEMBL23031994 | 0.79 | RIPK1 (0.42) | HDAC1MAPTKDM4ETP53EPHX2 | |
| SCHEMBL15748044 | 0.78 | CYP3A4 (0.55) | HDAC1KMT2AKDM4EEPHX2ALDH1A1 | |
| SCHEMBL27353844 | 0.78 | HPGDS (0.49) | ERCC1ERCC4HDAC1KMT2AMAPT | |
| SCHEMBL22009219 | 0.78 | TSHR (0.39) | HDAC1KMT2ALMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094525-A1 | IMPROVED ANTIBODY-PAYLOAD CONJUGATES (APCS) PREPARED BY SITE-SPECIFIC CONJUGATION UTILIZING GENETIC CODE EXPANSION | VERAXA BIOTECH GMBH (DE) | 2023-06-01 | — | — | WO | disclosed |