Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23032087 | 0.85 | LOXL2 (0.38) | LOXL2RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL23031761 | 0.84 | IDO1 (0.36) | CCR5IDO1ALDH1A1 | |
| SCHEMBL23031999 | 0.80 | RAB9A (0.34) | LOXL2RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL23031884 | 0.71 | RAB9A (0.35) | LOXL2RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL23031763 | 0.68 | IDO1 (0.38) | CHRM3CCR5IDO1ALDH1A1 | |
| SCHEMBL23014982 | 0.67 | LOXL2 (0.50) | LOXL2RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL23031872 | 0.67 | LOXL2 (0.43) | LOXL2RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL28887579 | 0.67 | LOXL2 (0.59) | LOXL2RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL3401155 | 0.66 | LOXL2 (0.56) | LOXL2RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL3722688 | 0.65 | HTT (0.51) | RAB9ANPC1SMN1; SMN2GAACHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034924-A1 | TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS | BIOGEN MA INC. (US) | 2021-02-25 | — | — | WO | disclosed |