Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | CCR5 | P51681 | 4/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23031761 | 0.84 | IDO1 (0.36) | IDO1CCR5AGERHTR2ATAAR1 | |
| SCHEMBL23032087 | 0.83 | LOXL2 (0.38) | IDO1CCR5CHRM3 | |
| SCHEMBL23032086 | 0.80 | IDO1 (0.32) | IDO1AGER | |
| SCHEMBL23032003 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL23031870 | 0.76 | IDO1 (0.47) | IDO1CCR5AGERHTR2ATAAR1 | |
| SCHEMBL23032002 | 0.69 | AGER (0.36) | IDO1AGER | |
| SCHEMBL23032084 | 0.68 | LOXL2 (0.36) | IDO1CCR5ALDH1A1CHRM3 | |
| SCHEMBL10458623 | 0.66 | IDO1 (0.50) | IDO1HTR2ATAAR1CHRM3RXRA | |
| SCHEMBL649020 | 0.65 | IDO1 (0.64) | IDO1HTR2ATAAR1RXRARXRB | |
| SCHEMBL9342895 | 0.65 | IDO1 (0.64) | IDO1HTR2ATAAR1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034924-A1 | TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS | BIOGEN MA INC. (US) | 2021-02-25 | — | — | WO | disclosed |