⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520806 | 1.00 | — | — | |
| SCHEMBL21242582 | 1.00 | — | — | |
| SCHEMBL12162660 | 0.78 | — | — | |
| SCHEMBL29634723 | 0.76 | — | — | |
| SCHEMBL25053929 | 0.76 | — | — | |
| SCHEMBL9684760 | 0.76 | KMT2A (0.34) | — | |
| SCHEMBL28137306 | 0.75 | CHRNB2 (0.41) | — | |
| SCHEMBL28152363 | 0.75 | CHRNB2 (0.41) | — | |
| SCHEMBL28151260 | 0.75 | CHRNB2 (0.41) | — | |
| SCHEMBL29567784 | 0.74 | KMT2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4038063-B1 | HETEROCYCLIC COMPOUNDS FOR INHIBITING TYK2 ACTIVITIES | BEIJING INNOCARE PHARMA TECH CO LTD (CN) | 2024-04-24 | — | — | EP | disclosed |
| US-11578058-B2 | Heterocyclic compounds for inhibiting TYK2 activities | Beijing Innocare Pharma Tech Co. (CN) | 2023-02-14 | — | — | US | disclosed |
| US-11578058-B2 | Heterocyclic compounds for inhibiting TYK2 activities | Beijing Innocare Pharma Tech Co. (CN) | 2023-02-14 | — | — | US | disclosed |
| CN-114650990-B | Heterocyclic compounds for inhibiting TYK2 activity | 北京诺诚健华医药科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-20220259184-A1 | HETEROCYCLIC COMPOUNDS FOR INHIBITING TYK2 ACTIVITIES | BEIJING INNOCARE PHARMA TECH CO. LTD. (CN) | 2022-08-18 | — | — | US | disclosed |
| EP-4038063-A1 | HETEROCYCLIC COMPOUNDS FOR INHIBITING TYK2 ACTIVITIES | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2022-08-10 | — | — | EP | disclosed |
| CN-114650990-A | Heterocyclic compounds inhibiting TYK2 activity | 北京诺诚健华医药科技有限公司 | 2022-06-21 | — | — | CN | disclosed |
| WO-2021254133-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-12-23 | — | — | WO | disclosed |
| WO-2021180072-A1 | HETEROCYCLIC COMPOUNDS FOR INHIBITING TYK2 ACTIVITIES | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-09-16 | — | — | WO | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |