SCHEMBL9684760

SCHEMBL9684760

NC(=O)C1CC(F)(F)C1(F)F

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.34
GRM4 Q14833 4/20 0.30
ALDH1A1 P00352 2/20 0.30
CYP1A2 P05177 2/20 0.30
CYP2C19 P33261 2/20 0.30
MEN1 O00255 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
GRM8 O00222 1/20 0.30
GRM6 O15303 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10704644 0.77 CYP2C19 (0.36) KMT2AGRM4ALDH1A1CYP1A2CYP2C19
SCHEMBL2520806 0.76
SCHEMBL23033142 0.76
SCHEMBL21242582 0.76
SCHEMBL10428300 0.75
Hydrochloric Acid SCHEMBL7755247 0.75 CYP2C19 (0.35) KMT2AGRM4ALDH1A1CYP1A2CYP2C19
SCHEMBL7755221 0.75 CHRNB2 (0.31)
SCHEMBL29567784 0.73 KMT2A (0.33) KMT2A
SCHEMBL12162660 0.72
SCHEMBL10943754 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4948879-A Monoazo compounds containing a fiber-reactive group and an oxazolopyridone or oxazinopyridone coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-14 US claimed
US-4065254-A DIAZO DYES, LEATHER, COTTON, WOOL CIBA-GEIGY CORPORATION (US) 1977-12-27 US claimed
US-5110746-A Method for the determination of albumin in biological fluids PHARMACIA DIAGNOSTICS INC. (US) 1992-05-05 US disclosed
US-4948879-A Monoazo compounds containing a fiber-reactive group and an oxazolopyridone or oxazinopyridone coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-14 US disclosed
WO-1988008533-A1 METHOD FOR THE DETERMINATION OF ALBUMIN IN BIOLOGICAL FLUIDS ELECTRO-NUCLEONICS, INC. (US) 1988-11-03 WO disclosed
EP-0287745-A1 Method for the determination of albumin in biological fluids SCHIAPPARELLI BIOSYSTEMS, INC. (US) 1988-10-26 EP disclosed
US-4224025-A Process for the dyeing and printing of paper materials in different hues using a single coupling component CIBA-GEIGY CORPORATION (US) 1980-09-23 US disclosed
US-4065254-A DIAZO DYES, LEATHER, COTTON, WOOL CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed